Cancer Gene Therapy

Format Post in Science BY David T. Curiel, Joanne T. Douglas

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Cancer Gene Therapy David T.Cancer Gene Therapy Textbook Curiel, Joanne T. Douglas
Type:	eBook
Released:	2004
Publisher:	Humana Press
Page Count:	502
Format:	pdf
Language:	English
ISBN-10:	1588292134
ISBN-13:	9781588292131

A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation. Topics of special interest include vector-targeting techniques, the lessons learned to date from clinical trials of cancer gene therapy, and the regulatory guidelines for future trials. Noninvasive techniques to monitor the extent of gene transfer and disease regression during the course of treatment are also discussed.