Protein Folding, Misfolding, and Disease: Methods and Protocols (Methods in Molecular Biology)
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Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. The Author of this Book is Andrew F. Hill, Kevin J. Barnham, Roberto Cappai, Stephen P. Bottomley In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. Array ISBN . This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Protein Folding, Misfolding, and Disease: Methods and Protocols (Methods in Molecular Biology) available in English. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.